Synaptic plasticity and neural circuit formation

Synapses are highly dynamic structures that remodel in response to experience, learning, and environmental changes. Plasticity at the synaptic level underlies the brain’s ability to store information and adapt to new circumstances. Understanding the mechanisms of synaptic plasticity is essential for deciphering learning and memory processes, as well as for developing interventions for neurodegenerative and psychiatric disorders where plasticity is impaired.

  • Long-term potentiation and depression
  • Circuit refinement during development
  • Synaptic pruning and formation
  • Structural plasticity of dendritic spines

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