Cellular Mechanisms Underlying Neurodegenerative Disorder
Neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Huntington’s, arise from complex cellular dysfunctions, including protein misfolding, mitochondrial deficits, oxidative stress, and cell death pathways. Understanding these mechanisms provides a foundation for developing targeted therapies, biomarkers, and strategies for early detection. Investigating these cellular pathways also offers insights into disease progression and potential neuroprotective interventions.
- Protein misfolding and aggregation
- Mitochondrial deficits and oxidative stress
- Autophagy and apoptosis mechanisms
- Cellular stress responses
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